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Yi-Chin Fong Selected Research

Integrin alphaVbeta3

10/2009Osteopontin increases migration and MMP-9 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells.
10/2009Stromal cell-derived factor-1/CXCR4 enhanced motility of human osteosarcoma cells involves MEK1/2, ERK and NF-kappaB-dependent pathways.
8/2009Glial cell-derived neurotrophic factor increases migration of human chondrosarcoma cells via ERK and NF-kappaB pathways.
6/2009Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway.
5/2009CTGF enhances migration and MMP-13 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells.
4/2009Leptin enhances cell migration in human chondrosarcoma cells through OBRl leptin receptor.
3/2009CCL5 increases lung cancer migration via PI3K, Akt and NF-kappaB pathways.
2/2009Stromal cell-derived factor-1 increase alphavbeta3 integrin expression and invasion in human chondrosarcoma cells.
2/2009Cyr61 increases migration and MMP-13 expression via alphavbeta3 integrin, FAK, ERK and AP-1-dependent pathway in human chondrosarcoma cells.
3/2008TGF-beta1 increases motility and alphavbeta3 integrin up-regulation via PI3K, Akt and NF-kappaB-dependent pathway in human chondrosarcoma cells.

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Yi-Chin Fong Research Topics

Disease

59Neoplasms (Cancer)
11/2021 - 08/2007
55Chondrosarcoma
11/2021 - 11/2004
42Neoplasm Metastasis (Metastasis)
11/2021 - 03/2008
15Osteosarcoma (Osteogenic Sarcoma)
11/2021 - 11/2008
13Osteoarthritis
06/2022 - 09/2007
7Rheumatoid Arthritis
12/2021 - 09/2007
6Inflammation (Inflammations)
01/2022 - 12/2011
4Obesity
01/2020 - 04/2009
4Arthritis (Polyarthritis)
01/2018 - 09/2007
3Infections
01/2022 - 05/2019
3Carcinogenesis
01/2016 - 04/2009
3Bone Resorption
10/2013 - 06/2008
3Lung Neoplasms (Lung Cancer)
06/2009 - 03/2009
2Breast Neoplasms (Breast Cancer)
01/2019 - 11/2014
2Hypoxia (Hypoxemia)
01/2017 - 11/2015
2Femoral Neck Fractures
06/2016 - 07/2009
2Osteoporosis
10/2013 - 06/2008
2Mitochondrial Diseases (Mitochondrial Disease)
02/2011 - 05/2010
2Mouth Neoplasms (Oral Cancer)
08/2009 - 08/2008
1Joint Dislocations
01/2022
1Immune System Diseases (Immune Disorders)
12/2021

Drug/Important Bio-Agent (IBA)

18IntegrinsIBA
11/2021 - 03/2008
18NF-kappa B (NF-kB)IBA
09/2010 - 03/2008
14Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2019 - 02/2009
13Matrix Metalloproteinases (MMPs)IBA
07/2021 - 09/2007
11Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 10/2014
10Integrin alphaVbeta3IBA
10/2009 - 03/2008
9CytokinesIBA
01/2022 - 06/2008
8Transcription Factor AP-1 (Transcription Factor AP 1)IBA
08/2021 - 09/2007
8Proteins (Proteins, Gene)FDA Link
07/2019 - 05/2009
7Interleukin-6 (Interleukin 6)IBA
01/2021 - 08/2008
7Small Interfering RNA (siRNA)IBA
01/2017 - 06/2008
7Monoclonal AntibodiesIBA
01/2012 - 09/2008
72- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA
01/2012 - 02/2009
6Messenger RNA (mRNA)IBA
11/2021 - 12/2008
6AdipokinesIBA
08/2021 - 01/2015
6LeptinIBA
08/2021 - 08/2008
6ResistinIBA
08/2021 - 01/2015
6AmphiregulinIBA
01/2020 - 05/2015
5LigandsIBA
11/2021 - 12/2011
5Vascular Endothelial Growth Factor CIBA
09/2021 - 01/2016
5Conditioned Culture MediaIBA
09/2021 - 06/2008
5ChemokinesIBA
01/2013 - 09/2007
5U 0126 (UO 126)IBA
01/2012 - 02/2009
4Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
06/2022 - 09/2014
4Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
01/2022 - 10/2014
4CC ChemokinesIBA
11/2021 - 03/2009
4erucylphosphocholineIBA
12/2019 - 01/2016
4Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2017 - 01/2013
4Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
11/2015 - 03/2008
4Chemokine CCL5IBA
11/2014 - 03/2009
4MAP Kinase Kinase Kinase 5IBA
07/2013 - 11/2008
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2013 - 06/2008
3Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 05/2019
3Biological ProductsIBA
09/2021 - 12/2017
3AdiponectinIBA
08/2021 - 10/2009
3Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
09/2020 - 01/2012
3Connective Tissue Growth FactorIBA
10/2017 - 05/2009
3OsteopontinIBA
10/2015 - 06/2009
32- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
12/2011 - 03/2008
3Integrin beta1IBA
09/2010 - 12/2008
3Integrin alpha2beta1IBA
02/2010 - 10/2009
3arginyl-glycyl-aspartic acidIBA
10/2009 - 02/2009
3Peptides (Polypeptides)IBA
10/2009 - 02/2009
3Chemokine CXCL12IBA
10/2009 - 09/2007
3Transforming Growth Factor beta1 (TGF beta 1)IBA
04/2009 - 03/2008
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2022 - 01/2018
2InterleukinsIBA
01/2022 - 06/2008
2EnzymesIBA
12/2021 - 12/2019
2Focal Adhesion Protein-Tyrosine KinasesIBA
11/2021 - 01/2017
2Nerve Growth Factor (NGF)IBA
11/2021 - 07/2021
2Matrix Metalloproteinase 2 (Gelatinase A)IBA
08/2021 - 07/2021
2Transcription Factors (Transcription Factor)IBA
08/2021 - 09/2007
2Nicotinamide PhosphoribosyltransferaseIBA
08/2021 - 09/2020
2ApelinIBA
01/2020 - 01/2020
2Biomarkers (Surrogate Marker)IBA
11/2019 - 05/2015
2Cysteine (L-Cysteine)FDA Link
07/2019 - 10/2017
2tanshinoneIBA
01/2018 - 12/2017
2Integrin alpha6beta1IBA
11/2017 - 05/2015
2matrigelIBA
11/2015 - 10/2014
2Adiponectin ReceptorsIBA
11/2015 - 10/2009
2AntioxidantsIBA
09/2014 - 10/2013
2Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
07/2013 - 11/2004
2Nerve Growth Factors (Neurotrophins)IBA
07/2013 - 01/2013
2trkB ReceptorIBA
07/2013 - 01/2013
2Antineoplastic Agents (Antineoplastics)IBA
06/2012 - 04/2012
2benzimidazoleIBA
04/2012 - 10/2011
2Mitogen-Activated Protein KinasesIBA
01/2012 - 02/2009
2Insulin-Like Growth Factor I (IGF-1)IBA
12/2011 - 06/2008
2Integrin beta3 (GPIIIa)IBA
08/2009 - 09/2008
2IsoflavonesIBA
11/2008 - 11/2008
2Interleukin-8 (Interleukin 8)IBA
08/2008 - 06/2008
1Interleukin-17 (Interleukin 17)IBA
06/2022
1MelatoninIBA
01/2022
1Hypoxia-Inducible Factor 1IBA
11/2021
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
11/2021

Therapy/Procedure

9Drug Therapy (Chemotherapy)
08/2021 - 05/2010
7Therapeutics
01/2019 - 08/2007
7Radiotherapy
01/2013 - 05/2010
2Replantation
11/2021 - 05/2019